Longevity & Biohacking

NAD+ precursor used to support cellular energy, DNA repair, and sirtuin activity.

Consolidates over 25 key nutrients including Vitamin D3, K2, Zinc, and Boron into one formula.

Precursor to glutathione, the body's master antioxidant; supports liver and lung health.

Amino acid that supports metabolic health, cardiovascular function, and longevity (based on recent primate/mouse studies).

Supports over 300 enzymatic reactions, muscle function, and energy production.

Micro-dosing lithium is associated with neuroprotection and mood stability.

Provides methylated and active forms of B vitamins for methylation support and energy.

Directs calcium to bones and away from arteries to prevent calcification.

Mitochondrial support and antioxidant protection for the heart.

Universal antioxidant that regenerates other antioxidants and supports glucose metabolism.

Hormone precursor that declines with age; supports immune function and bone density.

Supports joint health and has been associated with reduced all-cause mortality in large observational studies.

Supports skin hydration and joint lubrication.

Cardiovascular health, specifically reducing arterial plaque and improving blood pressure.

Anti-inflammatory and digestive support.

Potent anti-inflammatory and antioxidant.

Eye health and protection against blue light/macular degeneration.

Powerful carotenoid antioxidant that supports skin health and mitochondrial function.

Induces autophagy (cellular cleanup) and supports heart health.

Senolytic agent that helps clear out 'zombie' (senescent) cells.

Antioxidant and senolytic that works synergistically with other longevity compounds.

Activates Nrf2 pathway for detoxification and DNA protection.

Adaptogen for stress management and cortisol reduction.

AMPK activator and glucose-lowering agent with significant longevity data.

Essential amino acids to support muscle protein synthesis without the caloric load of whole protein.

For cognitive function, muscle maintenance, and cellular energy.

A comprehensive drink mix containing Creatine, Glucosamine, and various polyphenols.

Bryan uses this as a primary source of healthy fats and polyphenols, specifically oleocanthal, for cardiovascular health and inflammation reduction.

High-flavanol cocoa is used to support circulatory health, cognitive function, and skin health.

A clean, pea-based protein source used to maintain muscle mass while adhering to a vegan protocol.

The base of the 'Super Veggie' meal, providing fiber, plant protein, and anthocyanins.

Used in the Super Veggie to improve insulin sensitivity and digestion.

Included in the 'Green Giant' beverage for spermidine, chlorophyll, and nucleic acids.

A topping for the Super Veggie to provide Omega-3 and Omega-6 fatty acids and complete protein.

Core ingredient in Nutty Pudding for monounsaturated fats and creamy texture.

A pre-mixed version of Bryan's famous Nutty Pudding to ensure exact ratios of walnuts, macadamias, and flax.

Used in Nutty Pudding for flavor and blood sugar regulation.

A snack or topping for Nutty Pudding containing high-antioxidant blueberries and walnuts.

Used in Nutty Pudding for its high antioxidant content and potential to stimulate Urolithin A production.

A key component of Super Veggie for immune support and vitamin D precursors.

The primary volume component of Super Veggie, chosen for sulforaphane content.

Cruciferous vegetable in Super Veggie providing fiber and vitamin C.

Added to Super Veggie for its anti-inflammatory and pro-kinetic (digestive) properties.

Used in Super Veggie for cardiovascular health and immune support via allicin.

Bryan uses the Oura Ring as his primary device for tracking sleep stages, resting heart rate, and heart rate variability (HRV). It is essential for his data-driven approach to recovery.

Used to maintain optimal core body temperature throughout the night, which Bryan identifies as critical for maximizing Deep and REM sleep.

Continuous Glucose Monitoring (CGM) allows Bryan to see real-time blood sugar responses to every food in the Blueprint protocol.

Used as a secondary validation for recovery and to monitor cardiovascular strain during his daily 1-hour workouts.

Bryan uses this for segmental body composition (fat/muscle mass per limb) and to track Vascular Age via Pulse Wave Velocity.

To block the full spectrum of blue, green, and violet light in the evening to prevent melatonin suppression.

Bryan uses the H10 for the most accurate heart rate data during exercise, as chest straps outperform wrist sensors during movement.

Bryan targets a blood pressure of 110/70. Daily monitoring is essential to ensure his diet and supplements are maintaining this target.

Specifically used for facial skin health to reduce fine lines, wrinkles, and pigmentation as part of his 'Project Baby Face'.

Oral health is a pillar of Blueprint due to the link between gum disease and systemic inflammation/heart disease.

Used for Bryan's high-intensity interval training (HIIT) to maximize VO2 max, which is a top predictor of longevity.

Red and Near-Infrared (NIR) light therapy for mitochondrial health, skin rejuvenation, and reducing inflammation.

Used for non-invasive Vagus Nerve Stimulation (nVNS) to increase HRV and induce a state of parasympathetic calm.

Bryan maintains strict air quality standards (PM2.5 < 1) in his home to reduce systemic inflammation from pollutants.

Renue By Science sets the industry standard for transparency by providing batch-specific COAs for purity, heavy metals, and stability. Their pure powder form eliminates all fillers and offers the most cost-effective way to achieve high-dose NMN supplementation.

Thorne is the most trusted name in clinical-grade supplements, and NiaCel 400 uses Nicotinamide Riboside Malate for superior stability and absorption. The NSF Certified for Sport designation ensures it is free from contaminants and accurately labeled.

Tru Niagen is the flagship product for Nicotinamide Riboside (NR), backed by the company (ChromaDex) that holds the primary patents and has funded the majority of NR human trials. It is the most scientifically 'proven' NAD+ booster on the market.

ProHealth uses Uthever NMN, which is widely considered the highest quality branded NMN ingredient. They are one of the few companies that perform triple-testing on every batch to ensure zero degradation.

This is the most comprehensive senolytic formula on the market, utilizing a 'hit-and-run' dosing strategy (2 days a month) modeled after the Mayo Clinic protocols. It combines nine different senolytic compounds including Fisetin, Quercetin, and Luteolin in high-potency forms.

Life Extension offers the best value-to-science ratio by using Bio-Fisetin, which is formulated with galactomannans from fenugreek seeds to increase bioavailability by 25 times over standard fisetin.

Renue by Science specializes in liposomal delivery, which is arguably the most effective way to deliver hydrophobic senolytics like Fisetin directly into the bloodstream while bypassing first-pass metabolism.

Thorne is the gold standard for clinical purity. Their Quercetin Phytosome uses the Indena Quercefit delivery system, which is proven to be up to 20 times more bioavailable than standard quercetin.

This is the 'gold standard' for spermidine, derived from non-GMO European wheat germ. It is the specific formulation used in the SmartAge human clinical trials, proving its ability to trigger autophagy and improve cognitive markers.

Mitopure is a proprietary, highly pure form of Urolithin A, which specifically triggers mitophagy (the autophagy of damaged mitochondria). It is the only Urolithin A supplement with significant human clinical backing for muscle strength and cellular energy.

This formula combines Fisetin, Quercetin, and Apigenin to target senescent cells and induce autophagy. It uses a specialized galactomannan fiber to increase the bioavailability of Fisetin by up to 25 times.

For those seeking the highest dose of pure spermidine rather than a food extract, DoNotAge offers 8mg of Spermidine Trihydrochloride per capsule. This is significantly higher than most wheat germ extracts.

Stelo is the first FDA-cleared CGM specifically designed for non-insulin users, making it the premier choice for longevity enthusiasts. It utilizes the same high-accuracy sensor technology as the medical-grade G7 but optimized for metabolic health tracking without requiring a prescription.

The Libre 3 is the smallest, thinnest CGM on the market (the size of two stacked pennies), offering the highest clinical accuracy (7.9% MARD) available in a consumer-ready device. It provides minute-by-minute readings directly to a smartphone without the need for manual scanning.

The Dexcom G7 is the gold standard for ecosystem integration, allowing users to see their glucose data on Apple Watch, Garmin, and various longevity platforms simultaneously. It features a 30-minute warm-up time, the fastest in the industry.

The MitoPRO 300 is the gold standard for desktop panels, offering a unique four-wavelength blend (630nm, 660nm, 830nm, 850nm) that targets both surface skin health and deeper tissue recovery. It features high irradiance with low EMF and zero flicker, backed by comprehensive third-party testing.

The BIOMAX series is arguably the most powerful panel on the market, utilizing a patent-pending 7-band spectrum that includes 480nm (blue light) and 1060nm (near-infrared) for a comprehensive therapeutic effect. It is the choice for users seeking maximum irradiance and spectral diversity.

Hooga is the best entry-point for red light therapy, providing a reliable, high-irradiance device at a fraction of the cost of premium brands. It focuses on the two most clinically studied wavelengths: 660nm and 850nm.

The Plunge All-In is the industry standard for home cold immersion, featuring a powerful 1HP cooling system and a fully integrated filtration unit. It is one of the few units on the market that is UL-certified for safety, ensuring electrical components are safe for water immersion environments.

The Ice Barrel 500 offers a superior upright, fully insulated design that allows for a more natural 'fetal' position, which research suggests can improve the psychological 'grit' aspect of cold exposure. It is highly durable and features built-in steps and a seat.

The Morozko Forge is the only cold plunge on the market that actually produces its own ice, allowing for a true 32.1°F experience without ever needing to buy bags of ice. It is the gold standard for 'coldest' possible exposure.

Clearlight is the gold standard for infrared longevity due to its patented True Wave heaters that provide near, mid, and far-infrared while maintaining the lowest EMF and ELF levels in the industry. It features medical-grade construction with VOC-tested wood and non-toxic glues, ensuring no off-gassing during high-heat sessions.

Sunlighten mPulse is the only smart sauna with 3-in-1 SoloCarbon heaters that can be programmed to specific wavelengths for anti-aging, heart health, or recovery. Their technology is backed by specific clinical trials showing significant blood pressure reduction and core temperature increase.

For those following the Finnish longevity protocols (80-100°C), Finnleo provides the most authentic and high-quality traditional steam experience. Traditional saunas have the strongest long-term data regarding Heat Shock Protein (HSP) activation and dementia prevention.

The HigherDOSE blanket is the best entry-point for longevity enthusiasts who lack the space or budget for a full cabin. It uses far-infrared heat with low-EMF carbon heaters and incorporates layers of amethyst, tourmaline, and charcoal to enhance the detox experience.

The Oura Ring remains the gold standard for consumer sleep tracking due to its non-intrusive form factor and high-fidelity PPG sensors. It is the most utilized wearable in clinical sleep research, offering laboratory-level correlation for heart rate and respiratory metrics.

This is the best 'invisible' tracker that requires no wearable device. It uses ballistocardiography via a pneumatic sensor to detect heart rate, respiration, and movement with medical-grade precision.

The Apple Watch Series 9 features the most accurate heart rate sensor in the consumer market, outperforming Oura and Whoop in several independent validation tests. Its sleep stage algorithm is highly refined and integrates with a massive health ecosystem.

The Eight Sleep Pod 4 is the only device that both tracks sleep and actively improves it through dynamic temperature regulation. It is a cornerstone of the 'Blueprint' longevity protocol for maximizing deep sleep.