Adapalene Gel 0.1% Acne Treatment

Differin is the first FDA-approved prescription-strength retinoid (Adapalene) to be made available over-the-counter. It uses a highly stable, third-generation synthetic retinoid that is more photostable than retinol and backed by decades of clinical trials for both acne and photoaging. While it lacks the 'buffer' lipids of luxury serums, its pharmaceutical-grade efficacy and transparent 0.1% concentration make it the gold standard for value and performance.