01Gold Standard
Adapalene Gel 0.1%
$1515g tube
retinoidacneanti-aging
Only prescription-strength retinoid available OTC. FDA-approved for acne. Less irritating than tretinoin. Direct retinoic acid receptor binding—no conversion needed.
Quality Score12/12
Purity
Evidence
Transparency
Value
Strong Evidence
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Ingredients & Purity
Adapalene 0.1%—third-generation retinoid. Stable in sunlight.
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Scientific Evidence
FDA-approved. Can reduce acne by up to 87% in 12 weeks. Retinoids have highest dermatologist consensus for anti-aging.
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Brand Transparency
Pharmaceutical-grade manufacturing. Clear instructions.
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Value Assessment
$15/15g (30-day supply). Incredible value for prescription-grade retinoid.
Why Not Alternatives?
OTC retinol requires 2 conversion steps and is much weaker. This is prescription-grade at drugstore price. Tretinoin is stronger but Rx-only and more irritating.