Skincare

retinoids

01Gold Standard
12/12
Quality Score
Differin

Adapalene Gel 0.1%

$1515g tube
retinoidacneanti-aging

Only prescription-strength retinoid available OTC. FDA-approved for acne. Less irritating than tretinoin. Direct retinoic acid receptor binding—no conversion needed.

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Quality & Materials

Adapalene 0.1%—third-generation retinoid. Stable in sunlight.

Evidence & Testing

FDA-approved. Can reduce acne by up to 87% in 12 weeks. Retinoids have highest dermatologist consensus for anti-aging.

Brand Transparency

Pharmaceutical-grade manufacturing. Clear instructions.

Value Assessment

$15/15g (30-day supply). Incredible value for prescription-grade retinoid.

Why Not Alternatives?

OTC retinol requires 2 conversion steps and is much weaker. This is prescription-grade at drugstore price. Tretinoin is stronger but Rx-only and more irritating.

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