Apagard Premio
Apagard Premio is the gold standard for hydroxyapatite toothpaste, utilizing Sangi's proprietary Medical Hydroxyapatite (mHAP) which was the first of its kind approved by Japanese health authorities. It is specifically formulated to remineralize enamel, fill microscopic surface scratches, and remove plaque more effectively than standard fluoride pastes.
Ingredients & Purity
Contains a high concentration of mHAP (Medical Hydroxyapatite). Free from SLS and harsh abrasives. Uses xylitol for additional cavity protection.
Scientific Evidence
The mHAP ingredient was approved as an anti-caries agent in Japan in 1993. Multiple clinical trials confirm its ability to remineralize sub-surface enamel lesions.
Brand Transparency
Sangi is highly transparent about their R&D history and the specific manufacturing process of their hydroxyapatite particles.
Value Assessment
Priced at a premium ($16-$18 per tube), but the clinical efficacy for enamel repair justifies the cost for those with thinning enamel.
Why Not Alternatives?
Unlike many US-based 'nano-hydroxyapatite' brands that use generic or low-concentration powders, Sangi pioneered the technology and has decades of clinical data proving their specific particle size and concentration actually bonds to tooth enamel.